 Food with nutritional benefits may escape this objection.For example, GM rice has been tested for nutritional benefits, namely, increased levels of Vitamin A.

Árpád Pusztai published the first peer-reviewed paper to find negative effects from GM food consumption in 1999.Pusztai fed rats potatoes transformed with the "Galanthus nivalis" agglutinin (GNA) gene from the "Galanthus" (snowdrop) plant, allowing the tuber to synthesise the GNA lectin protein.