 Future studies will also need to investigate whether the ACH scaffolds allow for reinnervation of the target "in vivo" after a spinal cord injury.Hyaluronic acid (HA) is a widely used biomaterial as a result of its excellent biocompatibility and its physiologic function diversity.It is abundant in the extracellular matrix (ECM) where it binds large glycosaminoglycans (GAGs) and proteoglycans through specific HA-protein interactions.