 Furthermore, nerve regeneration with these conduits has yet to reach the level of functional recovery seen with nerve autografts.Collagen is a major component of the extracellular matrix, and it is found in the supporting tissues of peripheral nerves.A terpolymer (TERP) was synthesized by free radical copolymerization of its three monomers and cross-linked with collagen, creating a hybrid biological-synthetic hydrogel scaffold.