 Early cell adhesion is very important for preventing cell degeneration; the longer cells are suspended in culture, the more likely they are to degenerate.The purpose was to develop a biomaterial with good cell adherence and bioactivity with IKVAV, which is able to inhibit differentiation and adhesion of glial cells in addition to promoting neuronal cell adhesion and differentiation.The IKVAV peptide domain is on the surface of the nanofibers so that it is exposed and accessible for promoting cell contact interactions.