 A scene depicting the origin of the song in Sheldon's childhood is depicted in an episode of "Young Sheldon", which aired on February 1, 2018.It shows Sheldon's mother Mary singing the song to her son, who is suffering with the flu.In scenes set at Howard's home, he interacts with his rarely-seen mother (voiced by Carol Ann Susi until her death) by shouting from room to room in the house.