 From 1887, he was associated with the Hospice d'Ivry, and for years served as "chef de travaux" in the pathological anatomy laboratory of Victor André Cornil (1837–1908).In 1880, Gombault published an early description involving a type of hypertrophic neuritis that was later known as Dejerine–Sottas syndrome.With Charcot, he performed important research of obstructive biliary cirrhosis.