 His debut was for the Bengali film "Raj Dhanir Bookay" in 1960, and followed by numerous other Bengali and Urdu films, including "Chanda" (1962), "Talash (1963)", "Paisa" (1964), "Chakori (1967)" and "Bhaiya" (1966).After the release of the film "Tum Meray Ho", Ghosh moved to Karachi, Pakistan continuing to compose film music into the 1980s.He composed songs for the film "Aaina (1977)" one of the greatest films ever made in the Pakistani film industry.