 "A Grotesque Old Woman" (or "The Ugly Duchess") is perhaps the best-known of his works.It served as a basis for John Tenniel's depiction of the Duchess in "Alice's Adventures in Wonderland".It is likely a depiction of a real person with Paget's disease, though it is sometimes said to be a metaphorical portrait of the Margaret, Countess of Tyrol, who was known as "Maultasch", which, though literally translated "satchel mouth", was used to mean "ugly woman" or "whore" (because of her marital scandals).