 The population of Columbiana was 4,647 as of 2017.Columbiana is located at (33.183545, -86.609365).The city is located in the southeastern part of the county along Alabama State Route 25, which runs northeast to southwest to the west of the downtown area, leading northeast 9 mi (14 km) to Wilsonville and southwest 11 mi (18 km) to Calera.