 At the 2001 World Championships in Fukuoka, Japan, Van den Hoogenband won four silver medals in the 50 m, 100 m, 200 m freestyle events and 4×100 m freestyle relay.At the 2003 World Championships in Barcelona he split a 46.70 in the medley relay which stood as the fastest 100 m freestyle split until it was topped in 2008 by the French relay veteran Frédérick Bousquet, at 46.63 seconds.Van den Hoogenbands' 46.70, however, remained as the fastest textile relay split until it was topped in 2015 by Cameron McEvoy of Australia.