 The N-unprotected 2-stannylindoles generated from the Fukuyama Synthesis can be readily oxidized with iodine opening up an area of chemistry that allows for the synthesis of a variety compounds utilizing the 2-iodoindoles as a starting reagent.This iodine substituted derivative can lead to aryl halides, vinyl iodides, vinyl triflates, benzyl bromides.In addition to acetylenes (Sonogashira coupling), and acrylates (Heck reaction) in the second position.