 This phenomenon is called "electroporation" (or "electropermeabilization") and is becoming widely used to improve anticancer drug delivery into cells, which is being referred to as "electrochemotherapy".All biomedical applications of cell electropermeabilization use direct currents (all unipolar) with short and intense pulses (even though in vitro, time-decayed pulses can be used).Amplitude of the pulses depends on the tissues and on the shape and position of the electrodes, but, in vivo, in the case of the tumors, the amplitude of the electric pulses has to be high enough to establish an electrical field of 400 V/cm in the area of tumor (8 pulses with duration of 100 microseconds).