 One such example is the 2-iodoindole derivative, which can then lead to a variety of N-unprotected 2,3 substituted indoles.Before the discovery of this compound the chemistry involving 2-stannylindoles was not developed as there was no way to practically synthesis these N-unprotected 2,3-stannylindoles.One was limited to the production of N-protected 2-stannylindoles through metalation by a process known as Stille coupling.