 Both Interstate 40 and U.S. Route 70 traverse Ozone, connecting the area with Knoxville to the east and Nashville to the west.What is now Ozone was once situated along the stage route built in the late 18th century between Knoxville and Nashville.Around 1806, the widow of Elijah Haley, an early Cumberland settler, established a tavern in the Ozone area, and would later be instrumental in the establishment of Crab Orchard Inn a few miles to the west.