 His primary research and teaching interests were ancient art and material culture, women and gender in Antiquity, as well as Aristophanes and the Greek historians.Scaife was best known for his pioneering work in the use of computer technology in humanities scholarship.He was the founding editor of the Stoa Consortium for Electronic Publication in the Humanities in 1997, which serves as an umbrella project for many projects in the Classics, such as EpiDoc, the Suda on Line, Diotima and the Neo-Latin Colloquia.