 Significant and harmful residues of quinolones have been found in animals treated with quinolones and later slaughtered and sold as food products.There has been significant concern regarding the amount of flumequine residue found within food animals such as fish, poultry and cattle.In 2003 the Joint FAO/WHO Committee on Food Additives (JECFA) withdrew the maximum residue limits (MRLs) for flumequine and carbadox based on evidence showing both are direct acting genotoxic carcinogens, therefore the Committee was unable to establish an Acceptable Daily Intake (ADI) for human exposure to such residues.