 He scored music for a majority of V. Shantaram's films when the latter broke away from Prabhat to form his own film studio.Their relations soured in late 1950s after which Vasantrao Desai never worked for his former mentor again.He memorable songs are, Hindi Filmi Devotional song, "Ae Malik Tere Bande Ham" "Do Aankhen Barah Haath", 1957. and launched play back singer, Vani Jairam with the song, "Bole re papihara" in "Guddi" (1971).