 Within one review prulifloxacin was stated to have a similar tolerability profile to that of ciprofloxacin.Within another study it was found that prulifloxacin patients experienced a similar number of adverse reactions compared to those in the ciprofloxacin group (15.4% vs 12.7%).There were four serious adverse events in each treatment arm, including 1 death in the prulifloxacin arm.