 In 2005 he moved to become the Chair and John H. Hord professor of Pharmacology at Case Western Reserve University, where in 2016 he was appointed as Distinguished Professor of the Case Western Reserve University.In 2018 he joined University of California, Irvine, and is leading the Center for Translational Vision Research.He is the founder of two drug discovery companies, Polgenix and Retinagenix.