 On 15 June, he made his FIFA World Cup debut in a 2–1 defeat to Switzerland at the Estádio Nacional Mané Garrincha in Brasília.On June 25, 2014, Domínguez was named Man of the Match vs. France in Ecuador's final match at the 2014 FIFA World Cup.Domínguez kept a clean sheet and stopped shots from the likes of Karim Benzema, Paul Pogba, and Olivier Giroud.