 There are three possible stereoisomers around the azetidine ring, with the ("S","S")-(+) isomer being the most active, slightly more potent than LSD itself in drug discrimination tests using trained rats.There have been several unconfirmed reports of lysergic acid 2,4-dimethylazetidide being synthesized in illicit laboratories and distributed on blotter paper or in liquid solution under names such as "diazedine" and "λ".In 2013 LSZ also appeared on some designer drug and research chemical markets in the UK.