 At that time, Wiesner's research group corrected the stereochemistry of the methoxy group at C-1 from the β- to the α- configuration.Thus, any drawing of the delphinine molecule appearing before 1971–1972 is likely to show the incorrect stereochemistry at C-1.As a result of its early discovery and isolation in crystalline form (then considered a criterion of purity), the pharmacological properties of delphinine were extensively investigated in the 19th Century, despite the fact that its molecular structure was unknown.