 In 1503 Mong Yang Shans attacked and took the northern garrison town of Myedu that guarded the irrigated Mu valley, an important granary to the Bamar kingdom of Ava.These attacks culminated in a full scale invasion in 1524 and the establishment of Shan rule (1527–1555).The Kabaw Valley saw many an invasion by the kingdom of Manipur to the west, most notably during the reign of King Garibaniwaj (1709–1748) when his army crossed over the Chindwin and the Mu, took Myedu, and reached as far as Sagaing opposite the capital Ava.