 In February 2000, the then five-year-old Manistique earned her third Grade I victory in the Santa Maria Handicap while carrying a career-high 125 pounds.It was to be her last race as she later injured herself during a workout and was retired.Owner Marshall Naify died on April 19, 2000 and his estate sold Manistique to Aaron and Marie Jones who sent her to serve as a broodmare at Taylor Made Farm near Nicholasville, Kentucky.