 In the United States, prevalence is estimated at 240 per million and the annual incidence of scleroderma is 19 per million people.Likewise in the United States, it is slightly more common in African Americans than in their white counterparts, Scleroderma occurs much more often in women than it does in men.Choctaw Native Americans are more likely than Americans of European descent to develop the type of scleroderma that affects internal organs.