 The population was 435 at the 2010 census.Located along the historic Trail of Tears and on the Old Wire Road, Keetsville traced its official settlement to Georgia native John Cureton (1795-1853), who had served as a judge in Washington County, Arkansas before settling on the Washburn Prairie about two miles north of current day Washburn in 1840 and then procured the location of the town.In 1853, Cureton died and ownership of the land transferred to the Englishman James T. Keet (1818-1863), who then laid out the town of Keetsville.