 She was married to film director Amrutham who worked with her in films such as "Hudugaatada Hudugi" and "Kanasu Nanasu".The couple had a son, Abhishek, who married Sushma Srinivas, in 2009; and an adopted daughter, Abhinaya.Manjula started her acting career in 1965 with a drama troupe Prabhat Kalavidaru.