 On March 8, 2018, Goodwin signed a three-year, $20.3 million contract extension with the 49ers that will last through the 2021 season.In Week 6, against the Green Bay Packers, Goodwin set career-highs with 126 yards and two touchdowns.In the 2018 season, he finished with 23 receptions for 395 yards and four touchdowns.