 All constituents in a DCL are in equilibrium, and their distribution is determined by their thermodynamic stability within the DCL.The interconversion of these building blocks may involve covalent or non-covalent interactions.When a DCL is exposed to an external influence (such as proteins or nucleic acids), the equilibrium shifts and those components that interact with the external influence are stabilised and amplified, allowing more of the active compound to be formed.