 At the beginning of the 2014–15 season, Mathoho was part of a team that went 19 games without losing in the process, winning the MTN8 without conceding a goal and later won the league.He made his debut for South Africa on 14 May 2011 versus Tanzania in an international friendly.Mathoho played every minute of South Africa's successful AFCON qualifying campaign in 2014 under Ephraim Mashaba to help them qualify for the first time since 2008.