 She died in 1541, after Charles V had given her the title of Princess of Francavilla.On Ischia, Costanza established a circle of literary friends around her, among which were the poet Vittoria Colonna, the wife of her nephew, Sannazaro, Paolo Giovio, Tansillo and Bernardo Tasso.She also became a follower of Juan de Valdés and attended his lectures and discussions at his house in Chiaia.