 Romine hit .236/.304/.322 with 2 home runs and 16 RBIs in 174 at-bats during the 2016 season, and was a perfect 8-for-8 in stolen bases.He played eight different positions during the season, with 44 games at third base, 22 games in center field, 20 games at first base, 14 games at shortstop, 12 games at second base, two games at right field, one game at left field and one game at pitcher.Following the season, Romine was awarded the Bill McAdam 10th Man Award, as voted by Detroit Baseball Society
On January 13, 2017, the Tigers avoided arbitration with Romine, agreeing on a one-year, $1.3 million contract.