 Most or all of the components are also missing in some fungi, most notably the model organism "Saccharomyces cerevisiae".The presence of RNAi in other budding yeast species such as "Saccharomyces castellii" and "Candida albicans", further demonstrates that inducing two RNAi-related proteins from "S. castellii" facilitates RNAi in "S. cerevisiae".That certain ascomycetes and basidiomycetes are missing RNA interference pathways indicates that proteins required for RNA silencing have been lost independently from many fungal lineages, possibly due to the evolution of a novel pathway with similar function, or to the lack of selective advantage in certain niches.