 On 24 August 2010, Alexis joined Sevilla FC for €5 million, signing a six-year contract with the "Rojiblancos" as a replacement for Arsenal-bound Sébastien Squillaci.He appeared in 21 league games in his first year (26 overall) as the team finished fifth and qualified to the UEFA Europa League.In the third game of 2011–12 – his first – Alexis salvaged a point for Sevilla with an 86th-minute header away against Villarreal CF (2–2).