 They are used variously as antidepressants, anxiolytics, antiobsessionals, appetite suppressants, and entactogens.Azapirones such as buspirone, gepirone, and tandospirone are 5-HT1A receptor partial agonists marketed primarily as anxiolytics, but also as antidepressants.The antidepressants vilazodone and vortioxetine are 5-HT1A receptor partial agonists.