 Most SSDs are typically split into 4 KiB sectors, while most systems are based on 512 byte sectors with their default partition setups unaligned to the 4 KiB boundaries.The proper alignment does not help the SSD's endurance over the life of the drive; however, some Vista operations, if not disabled, can shorten the life of the SSD.Drive defragmentation should be disabled because the location of the file components on an SSD doesn't significantly impact its performance, but moving the files to make them contiguous using the Windows Defrag routine will cause unnecessary write wear on the limited number of P/E cycles on the SSD.