 The administrative center of this woreda is Selex Lexa; other towns in Medebay Zana include Debre Kerbe.Based on the 2007 national census conducted by the Central Statistical Agency of Ethiopia (CSA), this woreda has a total population of 125,028, an increase of 97,237 over the 1994 census, of whom 61,977 are men and 63,051 women; 10,526 or 8.42% are urban inhabitants.With an area of 2,685.12 square kilometers, Medebay Zana has a population density of 46.56 people per square kilometer, which is greater than the Zone average of 40.21.