 Many other novels have tuberculosis as a major plot element.For example, "The Constant Gardener" by John le Carré, and its movie adaptation directed by Fernando Meirelles, tells the tale of the testing of anti-tuberculosis drugs on unwitting subjects in Africa.Erich Maria Remarque's novel "Three Comrades" focuses on Patricia Hollman's love of life in light of her ultimately futile struggle with tuberculosis.