 PA 372 was designated in 1928 to run from McCall's Ferry, where a ferry crossed the Susquehanna River to York County and connected to an unpaved road leading to PA 74 in Kyleville, east to PA 41 (Newport Avenue) in Christiana.The route followed Pinnacle Road and Holtwood Road to Holtwood, its current alignment between Holtwood and Christiana, and Water Street, Bridge Street, and Sadsbury Avenue through Christiana.At this time, the entire length of PA 372 was paved.