 The first mention of Jews in Makhnivka came in 1648, in an account from the Cossack-Polish War (1648–57), when Chmielnicki's Cossacks attacked the local fortress and murdered a number of Poles and Jews.Over 100 years later, in 1765, six Jews are recorded in Makhnivka.Upon the Partition of Poland (), territories including western Ukraine were annexed into the Russian Empire.