 In his senior career he played for Genk, Standard Liège, Porto, Anderlecht, Burnley and Antwerp, winning a combined nine honours with the second and third clubs.Defour earned his first cap for Belgium in 2006, and represented the nation in the 2014 World Cup.Born in Mechelen, Defour played youth football with local KV Mechelen, moving to K.R.C.