 He was selected for the finals in Brazil by manager Marc Wilmots, making his debut in the competition on 26 June in the third group stage match against South Korea after Belgium had already won their first two outings and sealed qualification, and was sent off in the last minute of the first half of the eventual 1–0 success after a rash tackle on Kim Shin-wook.On 25 May 2018, 30-year-old Defour announced his retirement from international football.Belgium score listed first, score column indicates score after each Defour goal.