 From 1688, Neale developed his interests as a member of Parliament, and was successively MP for Petersfield(1668), Ludgershall (1679–89), Stockbridge (1689–90) and again for Ludgershall (1690–99), sitting on sixty-two committees.As an entrepreneur and speculator, he promoted building schemes, among which were Lower Shadwell and the converging streets of Seven Dials - one of them, Neal Street, Long Acre (street), still bears his name.Neal's Yard in Covent Garden is also named after him.