 The concrete forms that comprise the building were cast on site during a nearly four-year construction period using advanced techniques that were uncommon in America at the time.The building has been described as “both a serene setting for the contemplation of art and a contribution toward revitalizing the urban landscape of historic St. Louis.”

In June 2014 the building underwent an expansion project that would renovate storage and office spaces in the existing lower level to create two new public galleries.In consultation with Ando and his office, the Pulitzer increased the public space in the building from 6,800 square feet to roughly 10,400 square feet and reopened on May 1, 2015, with three concurrent solo exhibitions of artists Alexander Calder, Fred Sandback and Richard Tuttle.