 Comparative bioinformatic analyses showed that the size of the "L. infantum" BRCA2 protein is approximately three times smaller (125 kD) than its human counterpart.Furthermore, analyses revealed that LiBRCA2 possesses key features of the BRCA2 family.The smaller size of the "Leishmania" BRCA2 DNA repair protein has been exploited to better understand its function in homologous recombination and its interaction with the LiRAD51 recombinase.