 Mexican bootleggers supplied alcohol to the United States gangsters throughout the duration of the Prohibition in the United States, and the onset of the illegal drug trade with the U.S. began when the prohibition came to an end in 1933.Towards the end of the 1960s, Mexican narcotic smugglers started to smuggle drugs on a major scale.During the 1970s and early 1980s, Colombia's Pablo Escobar was the main exporter of cocaine and dealt with organized criminal networks all over the world.