 Anyway, even this pubertal MS could be more than one disease, because early-onset and late-onset have different demyelination patterns

Pediatric MS patients tend to have active inflammatory disease course with a tendency to have brainstem / cerebellar presentations at onset.Due to efficient repair mechanisms at early life, pediatric MS patients tend to have longer time to reach EDSS 6 but reach it at earlier age.An iron-responsive variant of MS has been reported in children.