 Balotelli exchanged squad number with teammate Greg Cunningham so he could continue to wear the number 45 shirt.On 19 August 2010, Balotelli came on as a substitute to score in his debut against Romanian side Politehnica Timișoara in a 1–0 away win in the UEFA Europa League, but during the match, injured the lateral meniscus in his right knee and on 8 September, underwent surgery that sidelined him until October.Balotelli eventually made his Premier League debut on 24 October as a substitute in a 3–0 home defeat to Arsenal, then made his first Premier League start on 30 October in a 2–1 away defeat to Wolverhampton Wanderers.