 For example, some diseases like Autoimmune GFAP Astrocytopathy or variants of CIDP that affects the CNS (CIDP is the chronic counterpart of Guillain–Barré syndrome) could be included.Autoimmune variants peripheral neuropathies or progressive inflammatory neuropathy could be in the list assuming the autoimmune model for MS, together with a rare demyelinating lesional variant of trigeminal neuralgia and some NMDAR Anti-NMDA receptor encephalitis

Venous induced demyelination has also been proposed as a hypothetical MS variant produced by CCSVI, Susac's syndrome and Neuro-Behçet’s disease(MS has an important vascular component), myalgic encephalomyelitis (aka chronic fatigue syndrome).Also leukoaraiosis can produce lesions disseminated in time and space.