 All of them nodal and paranodal proteins.Several anti-TNF drugs like adalimumab are commonly prescribed by a number of autoimmune conditions.Some of them have been reported to produce a CNS-demyelination compatible with, and by current knowledge indistinguishable from, standard MS. Several other monoclonal antibodies like pembrolizumab, nivolumab and infliximab have been also reported to produce MS artificially.