 Large-conductance mechanosensitive channel

The Large Conductance Mechanosensitive Ion Channel (MscL) Family (TC# 1.A.22) consists of pore-forming membrane proteins that are responsible for translating physical forces applied to cell membranes into electrophysiological activities.MscL has a relatively large conductance, 3 nS, making it permeable to ions, water, and small proteins when opened.