 However, the destruction of the Kingdom by the Ramadanid tribe and the subsequent rule by Muslim powers such as the Dulkadirids, the Mamluks and the Ottomans led to ever increasing numbers of Muslims in the region until finally the genocide removed the remaining vestiges of the Armenian people.There were also significant communities in parts of Trebizond and Ankara vilayets bordering Six vilayets (such as in Kayseri).After the Ottoman conquests many Armenians also moved west and settled in Anatolia, in large and prosperous Ottoman cities like Istanbul and Izmir.