 As its name suggests, this chemokine is selectively chemotactic for B cells belonging to both the B-1 and B-2 subsets, and elicits its effects by interacting with chemokine receptor CXCR5.CXCL13 and its receptor CXCR5 control the organization of B cells within follicles of lymphoid tissues.and is expressed highly in the liver, spleen, lymph nodes, and gut of humans.