 As of 2016, the institute had more than $80 million in bond debt from building its Novato headquarters in 1999 and completing its third building in 2012.It was leasing 27,000 sq ft of its campus to for-profit businesses, including BioMarin, Ultragenyx, Cellular Dynamics, An2H Discovery Limited, and Excel Venture Management.The Buck Institute's research program has ten focus areas related to geriatrics and longevity.