 Most of the currently known 2C compounds were first synthesized by Alexander Shulgin in the 1970s and 1980s and published in his book "PiHKAL" ("Phenethylamines i Have Known And Loved").Shulgin also coined the term 2C, being an acronym for the 2 carbon atoms between the benzene ring and the amino group.As of October 12, 2016, the 2C-"x" family of substituted phenethylamines is a controlled substances (Schedule III) in Canada.