 The main part of the campus and National Shrine Grotto of Our Lady of Lourdes are located to the west of the highway; the athletic complex, which includes Knott Arena, is to the east.North of Mount St. Mary's University, US 15 meets the southern end of US 15 Business (Seton Avenue) at a superstreet intersection that also serves Old Frederick Road; U-turn ramps on either side of the intersection provide the missing movements.The U.S. Highway crosses Toms Creek and Flat Run along the eastern side of the town of Emmitsburg before its interchange with MD 140 (Main Street).