 Son of Ludovico I of Saluzzo and Isabella of Montferrat, he succeeded him as marquis upon the latter's death in 1475.He continued his father's war against Charles I of Savoy, which had depleted Saluzzo's fortunes, but again without notable results.In 1481 he married his cousin, Giovanna Palaiologo of Montferrat, daughter of William VIII, Marquess of Montferrat.