 Her family was initially shocked by her decision to become a Catholic; it would take years for a reconciliation with them to take place.Von Speyr proceeded to form friendships with many notable Catholic thinkers, including Romano Guardini, Hugo Rahner, Erich Przywara, Henri de Lubac, Reinhold Schneider, Annette Kolb, and Gabriel Marcel.Meanwhile, her medical practice was very successful; she had as many as 60 to 80 patients a day.