 If this symporter did not exist, individual sodium channels and glucose uniporters would not be able to transfer glucose against the concentration gradient and into the bloodstream.Na+/K+/2Cl− symporter in the loop of Henle in the renal tubules of the kidney transports 4 molecules of 3 different types; a sodium ion (Na+), a potassium ion (K+) and two chloride ions (2Cl−).Loop diuretics such as furosemide (Lasix) act on this protein.