 Piscasaw Creek originates in Walworth County, Wisconsin, and travels through McHenry and Boone counties until it meets the Kishwaukee River near Belvidere, Illinois.The mouth of the Piscasaw along the Kishwaukee is at a place traditionally known as Red Horse Bend.Piscasaw Creek is classified as a "Class A" drainage by the criteria established by the Illinois Environmental Protection Agency, signifying the small river's relative health with respect to waterborne nutrients and chemicals.