 This set of symptoms was not given a name until 30 years later, when the nephrologist Oliver Wrong more fully described the disease.Wrong had studied with Dent and chose to name the disease after his mentor.Dent's disease is a genetic disorder caused by mutations in the gene "CLCN5", which encodes a kidney-specific voltage-gated chloride channel, a 746-amino-acid protein (CLC-5) with 12 to 13 transmembrane domains.