 Typically, the ion(s) will move down the electrochemical gradient, allowing the other molecule(s) to move against the concentration gradient.The movement of the ion(s) across the membrane is facilitated diffusion, and is coupled with the active transport of the molecule(s).SGLT1 in the intestinal epithelium transports sodium ions (Na+) and glucose across luminal membrane of the epithelial cells so that it can be absorbed into the bloodstream.