 This is the basis of oral rehydration therapy.If this symporter did not exist, individual sodium channels and glucose uniporters would not be able to transfer glucose against the concentration gradient and into the bloodstream.Na+/K+/2Cl− symporter in the loop of Henle in the renal tubules of the kidney transports 4 molecules of 3 different types; a sodium ion (Na+), a potassium ion (K+) and two chloride ions (2Cl−).