 As the paragroup DE(xD,E), including DE*, is extremely rare, the majority of DE male lines fall into subclades of either D-CTS3946 or E-M96.D-CTS3946 is suggested to have originated in Africa, though its most widespread subclade, D-M174, likely originated in Asia – the only place where D-M174 is now found.E-M96 is more likely to have originated in East Africa.