 As in the previous edition of the tournament, Germany were once again eliminated in the semi-finals of the competition, following a 2–0 defeat to hosts France on 7 July.On 4 June 2018, Khedira was included in Joachim Löw's final 23-man squad for the 2018 FIFA World Cup.As Germany were eliminated in the group stage, Khedira was deemed as one of the weakest performers in the squad.