 But both these artists received their most important commissions from the wealthiest and most powerful of all patrons, the Vatican.When Michelangelo took up the Sistine Chapel commission, he was working within a space that had already been extensively decorated by other artists.Around the walls the "Life of Christ" and "Life of Moses" were depicted by a range of artists including his teacher Ghirlandaio, Raphael's teacher Perugino and Botticelli.