 Among Niccolò's translations is a piece from a medical treatise by Galen, of which the original text is lost.The Renaissance, and the fall of the Byzantine Empire (1453), were accompanied by an influx of Greek scholars and manuscripts to the West, allowing direct comparison between the Arabic commentaries and the original Greek texts of Galen.This New Learning and the Humanist movement, particularly the work of Linacre, promoted "literae humaniores" including Galen in the Latin scientific canon, "De Naturalibus Facultatibus" appearing in London in 1523.