 In 1888 she took her London degree of M.D., and from 1887 to 1902 was surgeon at the New Hospital for Women (now the Elizabeth Garrett Anderson Hospital, Euston Road) initially assisting Dr. Mrs. Anderson, and being senior surgeon from 1889.In 1887 she was appointed lecturer on forensic medicine to the Royal Free Hospital, in 1889 lecturer on midwifery, and in 1902 chief gynæcologist.Amongst her students was Helen Hanson who was so inspired by Scharlieb that she followed her example and became a medical missionary in India.