 However, an item correlating with reduced serum ALT activity could not be clarified.In 17 patients with chronic hepatitis C, there wore no significant Immunocal-related changes in liver function test or immunological parameters.These findings suggest that long-term supplement with Immunocal alone may be effective for patients with chronic hepatitis B, and a further clinical study that long-term combination therapy with Immunocal and other agents including interferon may be effective for those with chronic hepatitis C should be performed.