 In 1923, he helped found Damascus University and along with a group of veteran educators, translated its entire curriculum from Ottoman Turkish into Arabic.In 1925 Khoury joined Abd al-Rahman Shahbandar to found the People's Party, of which he became vice-president.Minister of Education from April to July 1926, he was elected member of the Syrian Constituent Assembly in 1928, then elected to the Syrian Parliament in 1932, reelected in 1936 (and president of the Parliament till 1939) and 1943 (and again president of the Parliament till 1944).