 In 2012, the VAPBA had endorsed the Democratic challenger to Representative Frank Wolf in the same district.Shortly before the 2014 election, Comstock's Democratic opponent, Fairfax County Supervisor John Foust, said that she had never had a “real job.” “Although he claims he was referring to her jobs in partisan politics,” stated the "Weekly Standard", “Comstock’s campaign attacked this as a sexist remark.” Comstock herself called the remark “offensive and demeaning.”

Comstock won the election on November 4, 2014, defeating Democrat John Foust with 56 percent of the vote.Comstock faced Democrat LuAnn Bennett, a real estate executive and ex-wife of former Virginia Congressman Jim Moran, in the 2016 election.