 (eds); 311-321 (1994)

Oxidative stress, a known activator of HIV replication in vitro, has a potential role as a cofactor of HIV disease progression.Arguments supporting the role of oxidative stress as a cofactor in HIV activation are summarized in this review.The role of intracellular antioxidants such as glutathione (GSH), and drugs and nutriceutical agents promoting GSH synthesis, are discussed.