 He was minister of Guatemala and Salvador to Ecuador from 1839 till 1845, and in 1846-1848 to Colombia, but resigned, and went to Curaçao in 1849, and in 1850 to the United States, where he resided till his death.The governments of Guatemala and Salvador appointed him, in 1855, their minister to Washington, and for a long time he was dean of the diplomatic corps.Irisarri continued his literary work in the United States, and was generally esteemed for his knowledge, genial character, and polished manners.