 Molecules have been made to operate in accordance with Boolean algebra that performs a logical operation based on one or more physical or chemical inputs.The field has advanced from the development of simple logic systems based on a single chemical input to molecules capable of carrying out complex and sequential operations.Chemosensors have been incorporated through surface functionalization onto particles and beads such as metal based nanoparticles, quantum dots, carbon-based particles and into soft materials such as polymers to facilitate their various applications.