 from plant steroids, and established Mexico as a world center for steroid production in the years immediately after World War II.The discovery of the Marker degradation allowed the production of substantial quantities of steroid hormones for the first time, and was fundamental in the development of the contraceptive pill and corticosteroid anti-inflammatory drugs.In 1999, the American Chemical Society and the Sociedad Química de México named the route as an International Historic Chemical Landmark.