 When encapsulated in liposome nanoparticle, staurosporine is shown to suppress tumors "in vivo" in a mouse model without the toxic side effects which have prohibited its use as an anti-cancer drug with high apoptotic activity.Researchers in UC San Diego Moores Cancer Center develop a platform technology of high drug-loading efficiency by manipulating the pH environment of the cells.When injected into the mouse glioblastoma model, staurosporine is found to accumulate primarily in the tumor via fluorescence confirmation, and the mice did not suffer weight loss compared to the control mice administered with the free compound, an indicator of reduced toxicity.