 In the 17th century, it housed a court garden for medicinal herbs, and later the court of Eudoxia Lopukhina, estranged first wife of Peter I.Thus, the main street (now Bolshaya Pirogovskaya) was called "Tsarytsinskaya".In the late 18th century, Trubetskoy, Apraksin and other families set their country estates in Devichye Pole; the place remained a quiet country until the 1880s.