 In 1999, he helped to create the Penny Severns Breast and Cervical Cancer Research Fund, named after the late Penny Severns who died of breast cancer in 1998.He also advocated for legislation to increase the Rural Bond Bank's bond authorization and the maximum amount used to purchase securities issued by certain units of local government, ushered the creation of the Downstate Illinois Sports Facilities Authority through the Senate and wrote the Electronic Transfer Act.During his time in the Illinois Senate, Demuzio represented the 49th district, located in southwestern Illinois.