 Serbian-Greek relations have traditionally been friendly due to cultural and historical factors.Friendly relations have played an important role in bilateral relations between the two nations, especially during the wars of the 1990s and the Balkans Campaign in World War I.

Greece is the top investor in Serbian economy and during the NATO bombing of Yugoslavia, Greece openly expressed its disapproval and polls revealed that 94% of the Greek population were completely opposed to the bombing.Following the dissolution of the state union of Serbia and Montenegro, Serbia inherited the rights and obligations of the union and, as a result, the existing bilateral contractual framework with Greece.