 Matching up against the Tampa Bay Lightning in the first round, Pittsburgh lost the series in seven games; Letang had four assists.On January 23, 2012, Letang made the NHL 2012 All-Star roster as an injury replacement for Dustin Byfuglien, joining teammates Evgeni Malkin and James Neal.In their first round loss to the Stanley Cup playoffs against the Philadelphia Flyers, Letang scored one goal and had two assists  while earning a game misconduct in Game 3 for fighting Kimmo Timonen.