 Wong has received the Arthur C. Cope Award by the American Chemical Society.Additional awards include the Wolf Prize in Chemistry,  Royal Society of Chemistry Robert Robinson Award, Searle Scholar Award, Presidential Young Investigator Award, IUPAC International Carbohydrate Award, American Chemical Society Harrison Howe Award, American Chemical Society Claude S. Hudson Award, International Enzyme Engineering Award, the United States Presidential Green Chemistry Award, the F.A.Cotton Medal for Excellence in Chemical Research, and the American Chemical Society Award for Creative Work in Synthetic Organic Chemistry.