 Wong continued his postdoctoral research work with George M. Whitesides at Harvard University from 1982 to 1983, then began his independent career at Texas A&M University in the Chemistry Department.During his tenure at Texas A&M University, he went through the ranks including Assistant Professor, Associate Professor, and Professor of Chemistry.Wong was appointed as the Ernest W. Hahn Chair and Professor of Chemistry at the Scripps Research Institute and while he was a faculty member at Scripps, he also served as head of the Frontier Research Program on Glycotechnology at Riken in Japan and Director of the Genomics Research Center at Academia Sinica, and was later appointed by the President of the Republic of China (Taiwan) as the President of Academia Sinica.