 After his wife's death in 1814 he married secondly the Honourable Jane Butler, daughter of James Butler, 9th Baron Cahir and Sarah Nicholls, and sister of Richard Butler, 1st Earl of Glengall.They had one son, John Manners-Sutton.Lord Manners died in May 1842, aged 86, and was succeeded in the barony by his only son, John.