 Common psychological reactions to cancer (same) diagnosis and treatment include depressive symptoms and anxiety.Factors that may contribute to clinically significant anxiety and depression in the context of cancer include threat to life, uncertainty regarding prognosis and treatment outcome, worry regarding toxic treatments, functional impairment as a result of toxic treatments, and physical symptoms themselves, commonly including fatigue, pain, nausea, hair loss, neuropathy, and chemo brain.These topics have been incorporated into psychotherapy treatments tailored to the experience of living with cancer.