 Mirehouse was built in 1666 by Charles Stanley, 8th Earl of Derby, who sold it in 1688 to his agent, Roger Greg.The Greg family and then their descendants, the Storys owned the estate until 1802 when Thomas Story left it in his will to John Spedding.The Spedding family, who still own the house, have enlarged the house several times, with the last major changes occurring in the 1960s, when extensive renovation work was carried out, and in the 1980s, when the ground floor and grounds were opened to the public.