 A primary cause was the donning agent used for latex gloves prior to the 1990s, however most gloves now use protein free starch as a donning agent.There appears to be an association of rheumatoid arthritis (RA) both with gluten sensitive enteropathy (GSE) and gluten allergies.RA in GSE/CD may be secondary to tissue transglutaminase (tTG) autoimmunity.