 Saumur was the centre of Amyraldism, a distinctive form of Calvinism taught by Moses Amyraut but inspired by John Cameron (1580–1625), a Scot from Glasgow.This was a period of intense conflict over religion; the 1562-1598 French Wars of Religion caused around three million deaths from war and disease, surpassed only by those of the 1618-1648 Thirty Years' War, one of the most destructive conflicts in recorded history, with an estimated eight million, mostly inhabitants of the Holy Roman Empire.In Britain, similar arguments over religious practices would ultimately lead to the 1638-1652 Wars of the Three Kingdoms.