 He also spent time in the minor leagues, going 4-2 with a 2.37 ERA for Triple-A Louisville.On December 17, 2011, Vólquez, Yonder Alonso, Yasmani Grandal, and Brad Boxberger were traded by the Reds to the San Diego Padres for Mat Latos.Vólquez was the Padres' Opening Day starter for the 2012 season, losing 5–3 to the Los Angeles Dodgers.