 He is also Professor of Tumour Suppressor Biology at the Department of Microbiology, Tumor and Cell Biology at the Karolinska Institute where he is heading a research group.Lane has published more than 350 research articles that have been cited over 100,000 times and is internationally recognised for his original discovery of the p53 protein SV40 T antigen complex and for his many subsequent contributions to the p53 field.The p53 gene is the most frequently altered gene in human cancer with more than half of all cancers having mutant p53.