 Iowa State leads the series 50–48–4 through the 2018 season.Missouri and Iowa State first met in 1896 and the regional rivalry was born.Before the 1959 match-up between the two schools, which took place in Ames, Iowa, field testing showed that the telephones the two schools used to communicate with their coaches in the coaches box were wired so that either school could hear what was happening on the other sideline.