 Bertaina made his major league debut on August 1, 1964 against the Kansas City Athletics at Municipal Stadium.He started and gave up two earned runs in seven innings pitched, but did not receive a decision in the 5–2 Orioles victory.With Baltimore and Washington in 1967 he went 7–6 with a 2.99 ERA and a career-high 86 strikeouts, while tying for ninth in the American League with four shutouts.