 Stiripentol, can improve focal refractory epilepsy, as well as Dravet's syndrome, supplemented with clobazam and valproate was approved in Europe in 2007 as a therapy for Dravet syndrome and has been found to reduce overall seizure rate by 70%.In cases with more drug-resistant seizures, topiramate and the ketogenic diet are used as alternative treatments.Cannabidiol (CBD) was approved in United States for treatment of Dravet syndrome in 2018.