 Professor Debono was appointed consultant physician to the Lazaretto Isolation Hospital in 1942 (during the worst part of the Second World War), and was in charge of the polio patients until the post war epidemic was over.In 1963 he started an independent diabetic clinic and had continued for many years to serve as its director.In his article, "What every diabetic should know", Debono described a maintenance diet for diabetics that consisted of a low-calorie menu that would, if necessary, be supplemented through insulin injections.