 Wheeler was forced to withdraw from public life in the 1840s due to ill health, and she died in 1848 having refused invitations to take part in the revolution in France of that year.Wheeler's daughter Rosina Bulwer Lytton was a novelist and outspoken public speaker.Her grandson Robert Bulwer-Lytton, 1st Earl of Lytton, served as Viceroy of India from 1876 to 1880, and two of her great grandsons became the second and third Earls of Lytton.