 The Company's second largest export was tobacco.It also promoted the exploration and settlement of Venezuela's frontiers, most famously under the Expedition of the Limits, 1750-1761 headed by José de Iturriaga y Aguirre, which resulted in new settlements in Guayana Province.This growth was not experienced evenly, and the monopoly hurt small farmers, who continued to sell most of their product in the contraband trade.