 It is specifically defined as the ratio of area covered by Nissl-stained elements to area covered by unstained elements.More sophisticated cortical mapping techniques are still in the process of being developed and this field will most likely see an exponential growth in mapping methods in the near future.Neuromorphology has been used as a new method of exploring the underlying cause of many neurological disorders, and has been included in the clinical study of various neurodegenerative diseases, mental disorders, learning disabilities, and dysfunctions due to brain damage.