 With Inter, Anastasi won the 1977–78 Coppa Italia, making a substitute appearance in the final against Napoli, although his Inter performances were not as consistent or prolific as those with Juventus.As a result, he was sold to Ascoli in 1978, and he remained at the club for three more Serie A seasons, scoring 9 goals.In December 1979, he scored his 100th goal in Serie A in a 3–2 win over his former club, Juventus.