 "at Reliant Stadium, Houston, Texas"

Clad in all-blue uniforms for the first time in franchise history, Ron Dayne rushed for a career-high 153 yards and two touchdowns and Kris Brown kicked the winning 48-yard field goal as time expired to shock the Colts 27–24.The Texans used Dayne and rookie Chris Taylor to eat up the clock and exploit the Colts' suspect run defense, ranked last in the NFL, while taking pressure off David Carr and the struggling passing game.The win broke a nine-game losing streak to the Colts (11–4).