 Coming into the third quarter, Alex Smith completed a 48-yard touchdown pass to Antonio Bryant, but that was the final score for the 49ers.After a John Carney field goal, Reggie Bush took hold of a five-yard shovel pass from Drew Brees and scored his third touchdown of the night.In the fourth quarter, Bush ran down the sidelines and appeared to be heading for a fourth touchdown after a quick pass that he turned into a 74-yarder, but he fumbled the ball out of bounds.