 "at LP Field, Nashville, Tennessee"

The Titans opened the regular season at home against the New York Jets on September 10.After a scoreless first quarter, the Titans started to seriously trail as opposing RB Kevan Barlow scored on a one-yard TD run (extra point attempt was good) and an 8-yard TD pass to opposing WR Jerricho Cotchery (extra point attempt failed).In the third quarter, things didn't get any better, as opposing kicker Mike Nugent kicked an 18-yard field goal to make Tennessee trail 16–0.