 The eastern terminus of the state highway is at its signalized junction with State Route 7 approximately west of Proctorville near the northern banks of the Ohio River.SR 243 used to continue east from here, running concurrently with SR 7 into Proctorville, then split briefly from SR 7 as it passed through the community of Rome before ending at SR 7 about east of Proctorville.SR 243 between SR 7, in Proctorville, and SR 7 northeast of Proctorville, was signed in 1923 as SR 219.