 About 5–10% of asthmatics have aspirin hypersensitivity, but dietary salicylates have been shown not to contribute to this.The reactions in AERD (Samter's triad) are due to inhibition of the COX-1 enzyme by aspirin, as well as other NSAIDs that are not salicylates.Dietary salicylates have not been shown to significantly affect COX-1.