 As described in a 1983 publication, other scientists were able to get the ability to generate the enzymes to transfer from the "Flavobacterium" strain to a strain of "E. coli" bacteria via a plasmid transfer.There is scientific consensus that the capacity to synthesize nylonase most probably developed as a single-step mutation that survived because it improved the fitness of the bacteria possessing the mutation.More importantly, the enzyme involved was produced by a mutation completely randomizing the original gene.