 US 122 replaced the PA 42 designation south of Reading and the US 120 designation north of Reading and was routed to run concurrent with US 222 on Lancaster Avenue, Bingaman Street, and 5th Street between Morgantown Road and Center Street.In 1963, the US 122 concurrency was removed from US 222 in Reading as part of the elimination of US 122.By 1966, the PA 73 concurrency was removed from US 222 through Reading.