 Aside from the yerba mate harvest in the northeast, attempts to develop it suffered setbacks due to internal strife and lack of skill and machinery.The development of a cohesive state after 1852 led to the 1868 creation of Argentina's first Institute of Agronomy and the 1875 arrival of the first intact grain shipment from Argentina to Great Britain sparked a wave of local investment in cultivation and silos and British investment in railways and finance.The 1876 development of refrigerated beef shipping, likewise, led to the modernization of that sector.