 At the 2001 Mediterranean Games, he helped Greece win the silver medal at the tournament.In addition, Zisis won the gold medal with the Greek under-20 junior national team at the 2002 FIBA Under-20 European Championship, where he was also named the tournament's MVP.As a member of the senior men's Greek national basketball team, Zisis won the gold medal at the 2005 EuroBasket, which was held in Serbia and Montenegro.