 Al Khalifa was assigned the seat as Minister of Cabinet Affairs in September 2005.His portfolio included the Civil Service Bureau (CSB), Central Informatics Organisation (CIO), the e-Government Authority (EGA), Telecommunications including Telecommunications Regulatory Authority (TRA), Bahrain Internet Exchange (BIX) and the Bahrain Institute of Public administration (BIPA).He was heavily involved in the National Economic Strategy (NES) 2030 and was the leader for the Portfolio Office covering all programs and projects in his domain.