 Opioids are a class of drugs that can relax the body and relieve pain.In the United States, the National Institute on Drug Abuse (NIDA) reported that misuse of prescription opioids has dropped from 5.4% of college students in 2013 to 2.7% in 2018.Examples of prescription opioids include hydrocodone (Vicodin®), codeine, oxycodone (OxyContin®, Percocet®), and fentanyl.