 Among Rouse's best-known works were a biography of James Blair, founder and first president of the College of William and Mary; a history of the college president's house; and a popular chronicle of Williamsburg's history before and during its restoration as Colonial Williamsburg by John D. Rockefeller Jr., Abby Aldrich Rockefeller, and the Reverend Dr. W.A.R.Goodwin.In 1953, Parke Rouse became director of publications for the Colonial Williamsburg Foundation and worked closely with eventual president and chairman of the Foundation, Carlisle H. Humelsine.