 Disorder of the IL-19 production probably has an effect to different allergic reactions and other Th1 type athopic and skis pathogeneses, e.g.psoriasis .IL-19 also forms homologs with IL-20 and IL-24 and thus is able to bind the interleukin-20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3).