 The National Recording Registry announcement for this song said the song is "a signature distillation of the musical ideas and personality that inspired and influenced such New Orleans pianists as Fats Domino, Huey "Piano" Smith, James Booker, Dr. John and Allen Toussaint".According to Creswell, "Tipitina" "marshalled New Orleans rhythm into a sparkling package".The song has been widely covered as well as multiply recorded by Professor Longhair himself.