 Most of his masses are based on chansons, including works by Antoine Busnois, Alexander Agricola, Guillaume Dufay, Loyset Compère, and himself.Ghiselin also wrote motets, chansons, secular songs in Dutch, as well as some instrumental music.His setting of "La Spagna" for four parts is probably one of the earliest settings of this famous bassadanza tune for multiple parts, although its date has not been determined.