 It lies on Piazza Sant’Alessio 23, near the historical gardens of St. Alexius and Via di santa Sabina.Founded between the 3rd and 4th centuries, it was restored in 1216 by Pope Honorius III (some columns of his building survive in the present building's eastern apse); in 1582; in the 1750s by Tommaso De Marchis (his main altar survives); and between 1852 and 1860 by the Somaschi, which congregation still serves it as a rectory church.The 16th century style facade, elaborated from the De Marchis phase, is built onto the medieval-style quadriportico.