 Ottaviani's interest in writing science-related comics was inspired by Richard Rhodes's book "The Making of the Atomic Bomb".In discussing the book with comic book artist Steve Lieber, the two decided to write and illustrate a famous meeting between physicists Niels Bohr and Werner Heisenberg during World War II.That project expanded to include other stories from the history of science to become the graphic novel "Two-Fisted Science", including stories written by Ottaviani and illustrated by a variety of artists.