 The origins of the name are nebulous; most attribute it to a corruption of the term "a Cyro", perhaps referring in early days to a neighborhood resident.According to another theory "Acyro" refers to a corruption of the Latin word "circus", a stadium for horse racing, which was located in the vicinity.In 1540 Pope Paul III granted the church to the Confraternity of Orphans, and it was restored in 1588.