 One specific research topic of interest is how microbes such as "Pseudomonas aeruginosa" invade the eye and cause infection.Although the pathogenesis of microbial keratitis is not well understood, many different factors have been investigated.One group of researchers showed that corneal hypoxia exacerbated "Pseudomonas" binding to the corneal epithelium, internalization of the microbes, and induction of the inflammatory response.