 This is due to the production of short-chain fatty acids during the fermentation of plant-derived nutrients such as butyrate and propionate.Basically, the butyrate induces the differentiation of Treg cells by enhancing histone H3 acetylation in the promoter and conserved non-coding sequence regions of the FOXP3 locus, thus regulating the T cells, resulting in the reduction of the inflammatory response and allergies.The large intestine hosts several kinds of bacteria that can deal with molecules that the human body cannot otherwise break down.