 The DAP pathway is regulated at multiple levels, including upstream at the enzymes involved in aspartate processing as well as at the initial DHDPS catalysed condensation step.Lysine imparts a strong negative feedback loop on these enzymes and, subsequently, regulates the entire pathway.The AAA pathway involves the condensation of α-ketoglutarate and acetyl-CoA via the intermediate AAA for the synthesis of "L"-lysine.