 The average elevation of the municipality is 500 meters (1,625 feet) above sea level and the municipality covers an area of roughly .The municipality is bordered on the north by the municipalities of Tabasco and General Joaquin Amaro, on the east by the municipality of Calvillo, Aguascalientes, on the south by the municipalities of Jalpa and on the west by the municipality of Tlaltenango De Sanchez Roman.Huanusco was founded shortly after the Mixton War fought between 1540-1542 between the Caxcanes and other semi-nomadic Indigenous people of the area of north western Mexico against Spanish invaders, including their Aztec and Tlaxcalan allies.