 As an example, consider a neuron with a resting membrane potential of -70 mV (millivolts) and a threshold of -50 mV.It will need to be raised 20 mV in order to pass the threshold and fire an action potential.The neuron will account for all the many incoming excitatory and inhibitory signals via summative neural integration, and if the result is an increase of 20 mV or more, an action potential will occur.