 In 1846, Jones was elected to the U.S. House of Representatives as a Whig to represent Georgia's 3rd congressional district.He did not run for reelection in 1848, serving one term from March 4, 1847 through March 3, 1849.After his congressional term ended and another Whig took the seat, Jones moved to Oak Bowery, Chambers County, Alabama and practiced medicine in addition to serving on the board of the Oak Bowery Female College in 1850.