 On radio's "The Adventures of Sam Spade" she played just about every female role as well as Spade's secretary Effie Perrine.She appeared in such shows as "The Adventures of Ozzie and Harriet" and concurrently appeared on "The Great Gildersleeve" as the niece Marjorie Forrester.Tuttle had regular roles in such shows as "Brenthouse", "Dr. Christian", "Duffy's Tavern", "One Man's Family", "The Red Skelton Show" (as Junior's mother and as Daisy June, roles that she shared with Harriet Nelson), "Hollywood Hotel", and "Those We Love".