 As grandson of George of Bavaria, the young Otto Henry became regent of the new duchy of Palatinate-Neuburg after the Palatinate had lost the Landshut War of Succession against Albert IV, Duke of Bavaria.After the so-called "Kölner Spruch" (Verdict of Cologne) the duchy was created from the territories north of the Danube for Otto Henry and Philipp, the sons of Ruprecht of the Palatinate.While they were minors, their grandfather Philip, Elector Palatine, ruled the duchy until his death in 1508, followed by Elector Frederick II, their uncle.