 In subsequent years, and with the advent of the AIDS crisis, Howard Brown developed services including primary medical care, mental health counselling, substance abuse services, prevention and education, research programs and case management.Howard Brown Health Center, named for Dr. Howard Junior Brown, was incorporated in 1976 as Howard Brown Memorial Clinic.In the late 1970's, a high rate of hepatitis B among the center's patients inspired Howard Brown to participate in important research studies and vaccine trials against the disease, leading to the first hepatitis B vaccine.