 In plants, structural studies have suggested that the NLRs also oligomerise to form a structure called the resistosome, which also leads to cell death.It seems that in both plants and animals, the formation of the resistosome or the inflammasome, respectively, leads to cell death by forming pores in the membrane.It is inferred from protein structures that in plants the NLRs themselves are responsible for forming pores in the membrane, while in the case of the inflammasome, the pore-forming activity arises from gasdermin B which is cleaved by caspases as a result of the oligomerisation of the NLRs.