 The vast majority of plant lineages, except for certain algae, such as "Chlamydomonas", have NLRs.NLRs are also present in many animal species, however, they are not present in, for example, "Drosophila melanogaster" and Arthropods.Upon recognition of PAMPs by NLRs in animals, the NLRs oligomerise to form a structure known as the inflammasome, which activates pyroptosis.