 Under some circumstances, that descent could have made Reginald – until he definitely entered the clergy – a possible contender for the throne itself.In 1542 he was appointed as one of the three papal legates to preside over the Council of Trent, in 1549 he was appointed by Pope Paul III abbot of Gavello or Canalnuovo, and after the death of Pope Paul III in 1549 Pole, at one point, had nearly the two-thirds of the vote he needed to become pope himself at the papal conclave of 1549–50.His personal belief in justification by faith over works had caused him problems at Trent and accusations of heresy at the conclave.