 From 1615, Castine developed into a major fur trading post where French, English, and Dutch traders all fought for control.Sealskins, moose hides, and furs were traded by the Wabanakis for European commodities.By the early 1620s, warfare and introduced diseases, including smallpox, cholera and influenza, had decimated the tribes from Mount Desert Island southward to Cape Cod, leaving about 10 percent of the original population.