 If untreated, it can lead to the medical emergency of angle-closure glaucoma.In angle-closure glaucoma (also "closed-angle glaucoma", "primary angle-closure glaucoma", "acute glaucoma") the iris bows forward and causes physical contact between the iris and trabecular meshwork, which blocks the outflow of aqueous humor from within the eye.This contact may gradually damage the draining function of the meshwork until it fails to keep pace with aqueous production, and the intraocular pressure rises.