 Pfeiffer and Horton married in Santa Monica in 1981, and it was on their honeymoon that she discovered she had won the lead role in "Grease 2".Horton directed Pfeiffer in a 1985 ABC TV special, "One Too Many", in which she played the high school girlfriend of an alcoholic student (Val Kilmer); and in 1987, the real-life couple played an on-screen couple in the 'Hospital' segment of John Landis's comedy skit compilation, "Amazon Women on the Moon".In 1988, Pfeiffer was involved in an affair with John Malkovich, her co-star in "Dangerous Liaisons", who at the time was married to Glenne Headly.