 Triploidy is also utilized in salmon and trout farming to induce sterility.Rarely, autopolyploids arise from spontaneous, somatic genome doubling, which has been observed in apple ("Malus domesticus") bud sports.This is also the most common pathway of artificially induced polyploidy, where methods such as protoplast fusion or treatment with colchicine, oryzalin or mitotic inhibitors are used to disrupt normal mitotic division, which results in the production of polyploid cells.