 Pigmentary glaucoma (also, pigmentary dispersion syndrome) is caused by pigment cells sloughing off from the back of the iris and floating around in the aqueous humor.Over time, these pigment cells can accumulate in the anterior chamber in such a way that it can begin to clog the trabecular meshwork.It is a rare condition that occurs mostly among Caucasians, mostly males in their mid-20s to 40s, and most are nearsighted.