 Following Antony's Donations of Alexandria, which gave to Cleopatra the title of "Queen of Kings", and to their children the regal titles to the newly conquered Eastern territories, the war between Octavian and Mark Antony broke out.Octavian annihilated Egyptian forces in the Battle of Actium in 31 BCE.Mark Antony and Cleopatra committed suicide, leaving Octavianus the sole ruler of the Republic.