 Although modification of thebaine is the most common way of making thebacon, it is not uncommonly prepared by refluxing hydrocodone with acetic anhydride, generally similar to how diacetylmorphine is produced.It is also a product of the metabolism of hydrocodone by "Pseudomonas putida M10", the bacterium used for oil spill remediation.This also produces a morphinone reductase which can turn morphine into hydromorphone in a process which produces other active opioids, such as oxymorphone, oxymorphol, or hydromorphinol as intermediates.