 The alignment from Interstate 64 to US 60 was constructed in the 1970s as part of an upgrade that included US 60 that would act as an urban penetrator from Interstate 64 to Ashland, Kentucky.KY 180's former two-lane highway is now known as KY 3291 which ends at its intersection with Kentucky Route 3294 (formerly U.S. Route 60 Alternate and before that The Midland Trail) in the Ashland suburb of Cannonsburg.The Interstate 64 interchange previously featured higher-than-average accident levels.