 He started in the San Francisco 49ers' season-opener at the Dallas Cowboys and recorded six solo tackles and a pass deflection in their 28–17 victory.In Week 10, Bethea collected a season-high eight combined tackles, broke up a pass, and intercepted a pass by Drew Brees during a 27–24 overtime victory at the New Orleans Saints.On December 20, 2014, Bethea recorded a season-high tying eight combined tackles, two pass deflections, and returned an interception by Philip Rivers for a 49-yard touchdown during a 38–35 overtime loss to the San Diego Chargers in Week 16.