 US 17 and US 50 become a divided highway that crosses the Blue Ridge Mountains at Ashby Gap and enters Clarke County.The two highways descend the mountain to their crossing of the Shenandoah River at Berrys.US 17 and US 50 intersect SR 255 (Bishop Meade Road) south of Millwood and US 340 (Lord Fairfax Highway) in the hamlet of Waterloo south of the town of Boyce.