 Twelve miles (19.3 km) after SH-52, SH-16 joins up with U.S. Route 62/64, six miles (10 km) south of Haskell.Five miles (8 km) later, SH-162 branches off to the north, connecting with the town of Taft, and in another eight miles (13 km) enters the city of Muskogee along Okmulgee Street.In Muskogee, SH-16 meets U.S. Route 69 at 32nd Street, and turning north, forms a brief three-way concurrency (US-62/69/SH-16).