 (Medical Immunology, p. 117-122)

B cells are formed and mature in bone marrow (and spleen).It is a good mnemonic aide that B cells are formed in the bone marrow, but it is a mere coincidence since B cells were first studied in the chicken's bursa of Fabricius and it is from this bursa that B cells get their name.These B cells then leave the bone marrow and migrate to peripheral lymphoid tissues, such as a lymph node.