 It has been under the Royal patronage of the Spanish Crown since 1488, as authorized by Pope Innocent VIII.The college was founded in 1364 by the Cardinal Gil Alvarez De Albornoz (1310–1367) and built in 1365–1367.The Collegio was the model for the colleges founded at the University of Salamanca, starting in the late 14th century (notably the Colegio Viejo, 1401) and at other Spanish universities in the following couple of centuries.