 During his time as Chief of Station in Rome, and in the course of the ongoing anti-communist operations of the CIA in Italy, Karamessines was involved in events linked to the "Piano Solo", a plan for a coup d'état in the case of a communist election victory, drawn up by General de Lorenzo, then head of SIFAR and the Carabinieri.In this context he was involved in blackmail of political leaders from the Left, especially those linked to Aldo Moro.Under De Lorenzo's leadership of the SIFAR (1955-1962), the agency had opened dossiers on a total of 157,000 people, including mostly innocent citizens and politicians.