 Giddings built upon these sources to create GFS which would compare peptide mass data to entire genomes to identify the proteins.Giddings system is able to find new annotations of genes that have not been found, such as undocumented genes and undocumented alternative splice sites.In 2012 research was published where genes and proteins were found in a model organism that could not have been found without GFS because they had not been previously annotated.