 In 2004, the health issue leading to the highest YLD for both men and women was unipolar depression; in 2010, it was lower back pain.According to an article in "The Lancet" published in November 2014, disorders in those aged 60 years and older represent "23% of the total global burden of disease" and leading contributors to disease burden in this group in 2014 were "cardiovascular diseases (30.3%), malignant neoplasms (15.1%), chronic respiratory diseases (9.5%), musculoskeletal diseases (7.5%), and neurological and mental disorders (6.6%).