 He frequently worked with the same actors, either as a screenwriter, director or both - Ricardo Darín (4 times), Norma Aleandro (4 times), Federico Luppi (3 times), Antonella Costa (2 times), Vando Villamil (2 times), Roberto Vallejos (2 times) and Inés Estévez (2 times).Because of Mignogna's death in 2006 due to cancer, La señal - a film for which he had recently completed the writing of the script - he was not able to direct the movie.Its protagonist, Ricardo Darín, close friend and frequent collaborator, took over direction as a homage to Mignogna.