 For people with chronic fatigue syndrome, there is low quality evidence that rintatolimod can improve the quality of life.Rintatolimod is designed to boost cellular defenses against viruses and tumors, and could be synergistic with other anti-virals used for avian influenza.An independent review of rintatolimod trials in chronic fatigue syndrome was published in the December 2006 issue of the Journal of Clinical Virology.