 Lactacystin

Lactacystin is an organic compound naturally synthesized by bacteria of the genus "Streptomyces" first identified as an inducer of neuritogenesis in neuroblastoma cells in 1991.The target of lactacystin was subsequently to be to the proteasome on the basis for its affinity to certain catalytic subunits of the proteasome by Fenteany and co-workers in 1995.