 His primary philanthropic causes are the environment, social justice, and science, but he frequently contributes to historic projects and European museums.The Wyss Foundation, a charitable organization he founded, has awarded grants for environmental protection as well as to progressive policy organizations, including the Center for Budget and Policy Priorities, Health Leads, and the Constitutional Accountability Center.As of 2017, Wyss and the Wyss Foundation have donated more than $350 million to environmental protection, including conservation of national forests and other public lands in the Western United States.