 In 2018 he donated $1 Billion to the Wyss Campaign for Nature, aiming to conserve 30% of the worlds land and oceans by 2030.In 2007, he received the Harvard Business School Alumni Achievement Award, and in fall 2008, it was announced that Wyss donated the largest single endowment from one source in Harvard's history when he gave $125 million to found a multidisciplinary institute, the Wyss Institute for Biologically Inspired Engineering at Harvard University.In 2012–13, he announced the creation of the Campus Biotech and of its Wyss Center for Bio- and Neuro-engineering in Geneva, Switzerland.