 In 1899, he became a qualified lecturer in Clinical Medicine and Surgical Operations and, in 1903, was appointed as the Director of the Pius Institute for Crippled Children (Instituto dei Rachitici).He was the director of the orthopaedic clinic at the University of Milan for thirty five years.He was known for his work on congenital hip dislocation, scoliosis, skeletal tuberculosis and juvenile osteochondritis, and contributed to the pathological understanding of osteitis fibrosa cystica and achondroplasia.