 Neapolis was besieged by the Thasians unsuccessfully, causing the Athenians to praise them for their loyalty and for participating in the siege of Thasos itself in 410 or 409 BC.Around 350 BC, Philip II of Macedon took Neapolis and used it as Philippi's harbor.At the Battle of Philippi in 42 BC, the harbor was used as a base by the Republican leaders Brutus and Cassius.