 They cannot be predicted in particular by the scientist, but they are determined by the laws of nature and they are the singular causes of the natural development of dynamical structure.It is pointed out by W.T.Grandy Jr that entropy, though it may be defined for a non-equilibrium system, is when strictly considered, only a macroscopic quantity that refers to the whole system, and is not a dynamical variable and in general does not act as a local potential that describes local physical forces.