 Following his first loss Salgado made the move up to 118 pounds and made his debut at the weight in a title match against fellow Mexican Luis May for the interim WBC Youth Intercontinental bantamweight Title on 3 April 2004 at the Parque Andrés Quintana Roo in his native Cozumel.In front of a home crowd Salgado was triumphant after 10 rounds, winning a unanimous decision to take his first championship at the weight.In September 2010 José knocked out veteran Miguel Tique in rematch of their 2008 fight with a fourth round stoppage to win the vacant WBC Youth World super bantamweight title in his first fight at 122 pounds; an achievement that meant Salgado had now won minor titles in three different weight classes.