 The study concluded that most implanted devices were not required to submit data from clinical trials or scientific evidence of safety or effectiveness before they could be sold.In 2016, Center staff published a study in the peer-reviewed JAMA Internal Medicine about recently approved cancer drugs that had been criticized by other researchers as having no evidence that they decreased mortality or helped patients live longer.The Center’s follow-up study found no new evidence that any of the drugs affected survival, and only one of the drugs had clear evidence of improving patients’ quality of life.