 Despite its central location, Aclimação is one of the newer neighborhoods in downtown São Paulo, developed settled only in the 20th century.The neighborhood has grown up on a winding hilly triangular-shaped area of land known as the Sítio Tapanhoin, bounded on its three sides by the Caminho do Mar highway to the port of Santos and the Lavapés and Cambuci rivers.The land was purchased in 1892 by Carlos Botelho, a doctor born in Piracicaba and trained in Paris, who was anxious to pursue an ambition he had developed during his time in France to create a Brazilian equivalent of the "Jardin d’Acclimatation" in Paris, a place used for the acclimation of exotic species, with a research center for animal reproduction and hybridization and including a zoo among its various attractions.